How are heart researchers using the Nobel Prize-winning genetic scissors?

Article on the BHF Website

“We can all agree that 2020 has been a difficult year, but a silver lining was two women winning the Nobel Prize in Chemistry for developing the tools to edit DNA in living cells. Known as CRISPR-Cas9 (often shortened to CRISPR), their discovery of “genetic scissors” has revolutionised science as we know it and holds the promise of being able to treat or even cure diseases – from heart muscle problems to coronary heart disease.”

Click here for full article

Genetic modification research can lead to understanding how Genetic mutations take place and how we can use this understanding to our advantage for developing cures to faulty genetics in the future.

Current research includes looking into:

  • Congenital Heart Disease (University of Sheffield)
  • arrhythmogenic right ventricular cardiomyopathy (ARVC) (University of Keele)
  • thrombocytopenia – a condition where someone has low levels of platelets in their blood (University of Birmingham)
  • pulmonary arterial hypertension (PAH) (Imperial College, London)
  • heart damage after injury reparation (University of Oxford)

Read more….

BHF Research funding in general

 

 

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